3TU7
Human alpha-thrombin complexed with N-(methylsulfonyl)-D-phenylalanyl-N-((1-carbamimidoyl-4-piperidinyl)methyl)-l-prolinamide (BMS-189664)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | L | Prothrombin | polymer | 36 | 4096.5 | 1 | UniProt (P00734) Pfam (PF09396) In PDB | Homo sapiens (human) | Coagulation factor II, Activation peptide fragment 1, Activation peptide fragment 2, Thrombin light chain, Thrombin heavy chain |
| 2 | H | Prothrombin | polymer | 259 | 29780.2 | 1 | UniProt (P00734) Pfam (PF00089) In PDB | Homo sapiens (human) | Coagulation factor II, Activation peptide fragment 1, Activation peptide fragment 2, Thrombin light chain, Thrombin heavy chain |
| 3 | I | Hirudin variant-2 | polymer | 12 | 1548.5 | 1 | UniProt (P09945) UniProt (by SIFTS) (P01050) In PDB | Hirudo medicinalis (Medicinal leech) | |
| 4 | H | N-(methylsulfonyl)-D-phenylalanyl-N-[(1-carbamimidoylpiperidin-4-yl)methyl]-L-prolinamide | non-polymer | 478.6 | 1 | BIRD (PRD_000811) Chemie (0BM) | |||
| 5 | water | water | 18.0 | 44 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 35425.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 478.6 | |
| All* | Total formula weight | 35903.9 |
