3TU5

Actin complex with Gelsolin Segment 1 fused to Cobl segment

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Actin, alpha skeletal muscle	polymer	377	42097.0	1	UniProt (P68135) Pfam (PF00022) In PDB	Oryctolagus cuniculus (Rabbit)	Alpha-actin-1
2	B	Gelsolin,Protein cordon-bleu,Thymosin beta-4	polymer	297	32493.5	1	UniProt (P06396) UniProt (Q5NBX1) UniProt (P62328) Pfam (PF00626) Pfam (PF02205) Pfam (PF01290) In PDB	Homo sapiens (Human)	AGEL,Actin-depolymerizing factor,ADF,Brevin,T beta-4,Fx
3	A, B	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
4	A	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	1	Chemie (ATP)
5	A	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	2	Chemie (MPD)
6		water	water		18.0	65	Chemie (HOH)

Sequence modifications

B: 2 - 123 (UniProt: P06396)

PDB	External Database	Details
Met -17	-	initiating methionine
Asn -16	-	expression tag
His -15	-	expression tag
Lys -14	-	expression tag
Val -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
Ile -6	-	expression tag
Glu -5	-	expression tag
Gly -4	-	expression tag
Arg -3	-	expression tag
His -2	-	expression tag
Met -1	-	expression tag
Gly 0	-	expression tag
Ser 1	-	expression tag

B: 124 - 255 (UniProt: Q5NBX1)

PDB	External Database	Details
Val 128	Thr 1189	conflict

B: 256 - 279 (UniProt: P62328)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	74590.4
Non-Polymers*	Number of molecules	5
	Total formula weight	823.7
All*	Total formula weight	75414.1

*Water molecules are not included.