3TT3
Crystal Structure of LeuT in the inward-open conformation in complex with Fab
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Leucine transporter LeuT | polymer | 519 | 57909.3 | 1 | UniProt (O67854) Pfam (PF00209) In PDB | Aquifex aeolicus | |
2 | L | mouse monoclonal 1gG1 Fab fragment, heavy chain | polymer | 218 | 24208.6 | 1 | Mus musculus | ||
3 | H | mouse monoclonal 1gG1 Fab fragment, kappa light chain | polymer | 221 | 23985.9 | 1 | Mus musculus | ||
4 | A | octyl 1-thio-beta-D-glucopyranoside | non-polymer | 308.4 | 1 | Chemie (SOG) |
Sequence modifications
A: 1 - 513 (UniProt: O67854)
PDB | External Database | Details |
---|---|---|
Ala 268 | Tyr 268 | engineered mutation |
Ala 288 | Lys 288 | engineered mutation |
Val 354 | Thr 354 | engineered mutation |
Ala 355 | Ser 355 | engineered mutation |
Gly 514 | - | expression tag |
Thr 515 | - | expression tag |
Leu 516 | - | expression tag |
Val 517 | - | expression tag |
Pro 518 | - | expression tag |
Arg 519 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 106103.8 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 308.4 | |
All* | Total formula weight | 106412.2 |