3TOB
Human MOF E350Q crystal structure with active site lysine partially acetylated
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | histone acetyltransferase MYST1 | polymer | 303 | 35775.1 | 1 | UniProt (Q9H7Z6) Pfam (PF17772) Pfam (PF01853) | Homo sapiens (human) | MYST-1, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1, hMOF |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D (A) | water | water | 18.0 | 31 | Chemie (HOH) |
Sequence modifications
A: 177 - 458 (UniProt: Q9H7Z6)
| PDB | External Database | Details |
|---|---|---|
| His 156 | - | expression tag |
| His 157 | - | expression tag |
| His 158 | - | expression tag |
| His 159 | - | expression tag |
| His 160 | - | expression tag |
| His 161 | - | expression tag |
| Asp 162 | - | expression tag |
| Tyr 163 | - | expression tag |
| Asp 164 | - | expression tag |
| Ile 165 | - | expression tag |
| Pro 166 | - | expression tag |
| Thr 167 | - | expression tag |
| Thr 168 | - | expression tag |
| Glu 169 | - | expression tag |
| Asn 170 | - | expression tag |
| Leu 171 | - | expression tag |
| Tyr 172 | - | expression tag |
| Phe 173 | - | expression tag |
| Gln 174 | - | expression tag |
| Gly 175 | - | expression tag |
| Ser 176 | - | expression tag |
| Aly 274 | Lys 274 | microheterogeneity |
| Gln 350 | Glu 350 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35775.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 100.9 | |
| All* | Total formula weight | 35876.0 |
