3TL0
Structure of SHP2 N-SH2 domain in complex with RLNpYAQLWHR peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein phosphatase non-receptor type 11 | polymer | 109 | 12288.7 | 1 | UniProt (Q06124) Pfam (PF00017) | Homo sapiens (human) | Protein-tyrosine phosphatase 1D, PTP-1D, Protein-tyrosine phosphatase 2C, PTP-2C, SH-PTP2, SHP-2, Shp2, SH-PTP3 |
| 2 | B (B) | RLNpYAQLWHR peptide | polymer | 10 | 1439.5 | 1 | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | water | water | 18.0 | 23 | Chemie (HOH) |
Sequence modifications
A: 1 - 106 (UniProt: Q06124)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 13728.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 96.1 | |
| All* | Total formula weight | 13824.3 |
