3TKJ

Crystal Structure of Human Asparaginase-like Protein 1 Thr168Ala

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	L-asparaginase	polymer	319	33178.6	2	UniProt (Q7L266) Pfam (PF01112)	Homo sapiens (human)	Asparaginase-like protein 1, L-asparagine amidohydrolase
2	C, F (A, B)	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
3	D, G (A, B)	TRIS(HYDROXYETHYL)AMINOMETHANE	non-polymer		163.2	2	Chemie (TAM)
4	E, H (A, B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
5	I, J (A, B)	water	water		18.0	213	Chemie (HOH)

Sequence modifications

A, B: 2 - 308 (UniProt: Q7L266)

PDB	External Database	Details
Met -10	-	expression tag
Gly -9	-	expression tag
Gly -8	-	expression tag
Gly -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
Gly 0	-	expression tag
Gly 1	-	expression tag
Ala 168	Thr 168	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	66357.2
Non-Polymers*	Number of molecules	6
	Total formula weight	564.5
All*	Total formula weight	66921.7

*Water molecules are not included.