3TJF

Crystal Structure of human peroxiredoxin IV C51A mutant in reduced form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E (A, B, C, D, E)	Peroxiredoxin-4	polymer	254	28803.4	5	UniProt (Q13162) Pfam (PF00578) Pfam (PF10417)	Homo sapiens (human)	Peroxiredoxin IV, Antioxidant enzyme AOE372, AOE37-2, Prx-IV, Thioredoxin peroxidase AO372, Thioredoxin-dependent peroxide reductase A0372
2	F, G, H, I, J... (A, B, C, D, E)	SULFATE ION	non-polymer		96.1	15	Chemie (SO4)
3	U, V, W, X, Y (A, B, C, D, E)	water	water		18.0	794	Chemie (HOH)

Sequence modifications

A, B, C, D, E: 38 - 271 (UniProt: Q13162)

PDB	External Database	Details
Met 18	-	expression tag
Gly 19	-	expression tag
Ser 20	-	expression tag
Ser 21	-	expression tag
His 22	-	expression tag
His 23	-	expression tag
His 24	-	expression tag
His 25	-	expression tag
His 26	-	expression tag
His 27	-	expression tag
Ser 28	-	expression tag
Gln 29	-	expression tag
Asp 30	-	expression tag
Pro 31	-	expression tag
Leu 32	-	expression tag
Val 33	-	expression tag
Pro 34	-	expression tag
Arg 35	-	expression tag
Gly 36	-	expression tag
Ser 37	-	expression tag
Ala 51	Cys 51	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	144017.1
Non-Polymers*	Number of molecules	15
	Total formula weight	1440.9
All*	Total formula weight	145458.1

*Water molecules are not included.