3TFS

Ternary complex structure of DNA polymerase beta with a gapped DNA substrate and a, b dAMP(CFH)PP in the active site: Stereoselective binding of (S) isomer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	DNA polymerase beta	polymer	335	38241.7	1	UniProt (P06746) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791)	Homo sapiens (human)
2	B (T)	DNA (5'-D(*CP*CP*GP*AP*CP*TP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')	polymer	16	4844.1	1
3	C (P)	DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3')	polymer	10	3061.0	1
4	D (D)	DNA (5'-D(P*GP*TP*CP*GP*G)-3')	polymer	5	1536.0	1
5	E (A)	2'-deoxy-5'-O-[(S)-{(S)-fluoro[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}(hydroxy)phosphoryl]adenosine	non-polymer		507.2	1	Chemie (FHA)
6	F, G (A)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
7	H, I (A)	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
8	J, K, L, M (A)	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL)
9	N, O, P, Q (A, T, P, D)	water	water		18.0	356	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	47682.9
Non-Polymers*	Number of molecules	9
	Total formula weight	743.6
All*	Total formula weight	48426.5

*Water molecules are not included.