3TF6
Crystal structure of Neutrophil gelatinase-associated lipocalin (C87S mutant) in complex with Europium and the siderophore analog tren(cam)(1,2-hopo)2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Neutrophil gelatinase-associated lipocalin | polymer | 179 | 20613.5 | 3 | UniProt (P80188) Pfam (PF00061) | Homo sapiens (human) | NGAL, 25 kDa alpha-2-microglobulin-related subunit of MMP-9, Lipocalin-2, Oncogene 24p3, p25 |
| 2 | D, M, Q, R (A, C) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 3 | E, I, N (A, B, C) | EUROPIUM ION | non-polymer | 152.0 | 3 | Chemie (EU) | |||
| 4 | F, J, O (A, B, C) | 2,3-DIHYDROXY-BENZOIC ACID | non-polymer | 154.1 | 3 | Chemie (DBH) | |||
| 5 | G, K, P (A, B, C) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | H, L, S, T, U (A, B, C) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 7 | V, W, X (A, B, C) | water | water | 18.0 | 117 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 178 (UniProt: P80188)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Ser 87 | Cys 107 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 61840.5 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 1752.1 | |
| All* | Total formula weight | 63592.5 |
