3TEI
Crystal structure of human ERK2 complexed with a MAPK docking peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Mitogen-activated protein kinase 1 | polymer | 362 | 41444.6 | 1 | UniProt (P28482) Pfam (PF00069) In PDB | Homo sapiens (human) | MAP kinase 1, MAPK 1, ERT1, Extracellular signal-regulated kinase 2, ERK-2, MAP kinase isoform p42, p42-MAPK, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2 |
2 | B | Ribosomal protein S6 kinase alpha-1 | polymer | 24 | 2737.3 | 1 | UniProt (Q15418) In PDB | Homo sapiens | S6K-alpha-1, 90 kDa ribosomal protein S6 kinase 1, p90-RSK 1, p90RSK1, p90S6K, MAP kinase-activated protein kinase 1a, MAPK-activated protein kinase 1a, MAPKAP kinase 1a, MAPKAPK-1a, Ribosomal S6 kinase 1, RSK-1 |
3 | A | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
4 | water | water | 18.0 | 115 | Chemie (HOH) |
Sequence modifications
A: 1 - 360 (UniProt: P28482)
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Ala 77 | Arg 77 | engineered mutation |
Ala 314 | Glu 314 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 44181.9 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 506.2 | |
All* | Total formula weight | 44688.1 |