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3T9H

Kainate bound to a double cysteine mutant (A452C/S652C) of the ligand binding domain of GluA2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(B, D, F)
Glutamate receptor 2polymer25828883.53UniProt (P19491)
Pfam (PF10613)
Pfam (PF00060)
Rattus norvegicus (rat)GluA2, GluR2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2
2D, G, J
(B, D, F)
3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINEnon-polymer213.23Chemie (KAI)
3E, F, H, I, K
(B, D, F)
ZINC IONnon-polymer65.45Chemie (ZN)
4L, M, N
(B, D, F)
waterwater18.0571Chemie (HOH)
Sequence modifications
B, D, F: 4 - 117 (UniProt: P19491)
PDBExternal DatabaseDetails
Cys 63Ala 473engineered mutation
B, D, F: 120 - 261 (UniProt: P19491)
PDBExternal DatabaseDetails
Gly 118-linker
Thr 119-linker
Cys 140Ser 673engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight86650.4
Non-Polymers*Number of molecules8
Total formula weight966.7
All*Total formula weight87617.1
*Water molecules are not included.

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PDB entries from 2025-12-17

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