3T9D
Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with AMPPNP and 5-(PP)-IP5 (5-IP7)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Inositol Pyrophosphate Kinase | polymer | 330 | 37568.9 | 1 | UniProt (O43314) Pfam (PF18086) In PDB | Homo sapiens (human) | |
2 | A | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
3 | A | (1r,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate | non-polymer | 740.0 | 1 | Chemie (I7P) | |||
4 | A | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) | |||
5 | water | water | 18.0 | 338 | Chemie (HOH) |
Sequence modifications
A: 41 - 366 (UniProt: O43314)
PDB | External Database | Details |
---|---|---|
Gly 37 | - | expression tag |
Ser 38 | - | expression tag |
Phe 39 | - | expression tag |
Thr 40 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 37568.9 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 1367.7 | |
All* | Total formula weight | 38936.6 |