3T8X
Crystal structure of human CD1b in complex with synthetic antigenic diacylsulfoglycolipid SGL12 and endogenous spacer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | T-cell surface glycoprotein CD1b | polymer | 301 | 33482.7 | 2 | UniProt (P29016) Pfam (PF16497) Pfam (PF07654) | Homo sapiens (human) | |
| 2 | B, D (B, D) | Beta-2-microglobulin | polymer | 99 | 11748.2 | 2 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | Beta-2-microglobulin form pI 5.3 |
| 3 | E, G (E, G) | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 2 | In PDB GlyTouCan (G86851RC) | |||
| 4 | F (F) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 894.8 | 1 | In PDB GlyTouCan (G00395TQ) | |||
| 5 | H (H) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
| 6 | I, O, P, S, T (A, C, D) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 7 | J (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 8 | K, Q (A, C) | 2-O-sulfo-alpha-D-glucopyranosyl 2-O-hexadecanoyl-3-O-[(2E,4S,6S,8S)-2,4,6,8-tetramethyltetracos-2-enoyl]-alpha-D-glucopyranoside | non-polymer | 1065.5 | 2 | Chemie (T8X) | |||
| 9 | L, R (A, C) | tetracontane | non-polymer | 563.1 | 2 | Chemie (ULI) | |||
| 10 | M, N, U (B, D) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 11 | V, W, X, Y (A, B, C, D) | water | water | 18.0 | 525 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 280 (UniProt: P29016)
| PDB | External Database | Details |
|---|---|---|
| Ile 281 | - | expression tag |
| Asp 282 | - | expression tag |
| Lys 283 | - | expression tag |
| Leu 284 | - | expression tag |
| Gly 285 | - | expression tag |
| Gly 286 | - | expression tag |
| Gly 287 | - | expression tag |
| Leu 288 | - | expression tag |
| Asn 289 | - | expression tag |
| Asp 290 | - | expression tag |
| Ile 291 | - | expression tag |
| Phe 292 | - | expression tag |
| Glu 293 | - | expression tag |
| Ala 294 | - | expression tag |
| Gln 295 | - | expression tag |
| Lys 296 | - | expression tag |
| Ile 297 | - | expression tag |
| Glu 298 | - | expression tag |
| Trp 299 | - | expression tag |
| His 300 | - | expression tag |
| Glu 301 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 90461.7 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2200.1 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 4072.8 | |
| All* | Total formula weight | 96734.5 |
