3T04
Crystal structure of monobody 7c12/abl1 sh2 domain complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Tyrosine-protein kinase ABL1 | polymer | 123 | 13715.1 | 1 | UniProt (P00519) Pfam (PF00017) In PDB | Homo sapiens (human) | Abelson murine leukemia viral oncogene homolog 1, Proto-oncogene c-Abl, p150 |
| 2 | D | MONOBODY 7C12 | polymer | 103 | 11286.3 | 1 | Homo sapiens (human) | ||
| 3 | A, D | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 4 | D | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 127 | Chemie (HOH) |
Sequence modifications
A: 131 - 251 (UniProt: P00519)
| PDB | External Database | Details |
|---|---|---|
| Gly 129 | - | expression tag |
| Ser 130 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 25001.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 464.4 | |
| All* | Total formula weight | 25465.9 |
