3SZK

Crystal Structure of Human metHaemoglobin Complexed with the First NEAT Domain of IsdH from Staphylococcus aureus

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	D, A	Hemoglobin subunit alpha	polymer	141	15150.4	2	UniProt (P69905) Pfam (PF00042) In PDB	Homo sapiens (human)	Alpha-globin, Hemoglobin alpha chain
2	B, E	Hemoglobin subunit beta	polymer	146	15890.2	2	UniProt (P68871) Pfam (PF00042) In PDB	Homo sapiens (human)	Beta-globin, Hemoglobin beta chain, LVV-hemorphin-7
3	F, C	Iron-regulated surface determinant protein H	polymer	164	18904.8	2	UniProt (Q8NW39) Pfam (PF05031) In PDB	Staphylococcus aureus	IsdH, Haptoglobin receptor A, Staphylococcus aureus surface protein I
4	D, B, E, A	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	4	Chemie (HEM)

Sequence modifications

F, C: 86 - 229 (UniProt: Q8NW39)

PDB	External Database	Details
Gly 66	-	expression tag
Ser 67	-	expression tag
Ser 68	-	expression tag
His 69	-	expression tag
His 70	-	expression tag
His 71	-	expression tag
His 72	-	expression tag
His 73	-	expression tag
His 74	-	expression tag
Ser 75	-	expression tag
Ser 76	-	expression tag
Gly 77	-	expression tag
Leu 78	-	expression tag
Val 79	-	expression tag
Pro 80	-	expression tag
Arg 81	-	expression tag
Gly 82	-	expression tag
Ser 83	-	expression tag
His 84	-	expression tag
Met 85	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	99890.8
Non-Polymers*	Number of molecules	4
	Total formula weight	2465.9
All*	Total formula weight	102356.7

*Water molecules are not included.