3SYT
Crystal structure of glutamine-dependent NAD+ synthetase from M. tuberculosis bound to AMP/PPi, NAD+, and glutamate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Glutamine-dependent NAD(+) synthetase | polymer | 680 | 74855.4 | 4 | UniProt (P0A5L6) Pfam (PF00795) Pfam (PF02540) UniProt (by SIFTS) (P9WJJ3) | Mycobacterium tuberculosis | NAD(+) synthase [glutamine-hydrolyzing] |
| 2 | E, J, N, S (A, B, C, D) | GLUTAMIC ACID | non-polymer | 147.1 | 4 | Chemie (GLU) | |||
| 3 | F, K, P, T (A, B, C, D) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 4 | G, L, Q, U (A, B, C, D) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 4 | Chemie (AMP) | |||
| 5 | H, M, R, V (A, B, C, D) | PYROPHOSPHATE 2- | non-polymer | 176.0 | 4 | Chemie (POP) | |||
| 6 | I, O (A, C) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | W, X, Y, Z (A, B, C, D) | water | water | 18.0 | 486 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 679 (UniProt: P0A5L6)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 299421.7 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 5519.1 | |
| All* | Total formula weight | 304940.8 |
