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3SW7

Crystal Structure of the CDK2 in complex with thiazolylpyrimidine inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ACyclin-dependent kinase 2polymer29934002.51UniProt (P24941)
Pfam (PF00069)
In PDB
Homo sapiens (human)Cell division protein kinase 2, p33 protein kinase
2AN~4~-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-N~1~,N~1~-dimethyl-2-nitrobenzene-1,4-diaminenon-polymer370.41Chemie (19K)
3waterwater18.0144Chemie (HOH)
Sequence modifications
A: 1 - 298 (UniProt: P24941)
PDBExternal DatabaseDetails
Ace 0-ACETYLATION
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34002.5
Non-Polymers*Number of molecules1
Total formula weight370.4
All*Total formula weight34373.0
*Water molecules are not included.

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PDB entries from 2024-07-17

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