3SW7
Crystal Structure of the CDK2 in complex with thiazolylpyrimidine inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Cyclin-dependent kinase 2 | polymer | 299 | 34002.5 | 1 | UniProt (P24941) Pfam (PF00069) In PDB | Homo sapiens (human) | Cell division protein kinase 2, p33 protein kinase |
2 | A | N~4~-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-N~1~,N~1~-dimethyl-2-nitrobenzene-1,4-diamine | non-polymer | 370.4 | 1 | Chemie (19K) | |||
3 | water | water | 18.0 | 144 | Chemie (HOH) |
Sequence modifications
A: 1 - 298 (UniProt: P24941)
PDB | External Database | Details |
---|---|---|
Ace 0 | - | ACETYLATION |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 34002.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 370.4 | |
All* | Total formula weight | 34373.0 |