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3SW4

Crystal Structure of the CDK2 in complex with thiazolylpyrimidine inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ACyclin-dependent kinase 2polymer29934002.51UniProt (P24941)
Pfam (PF00069)
In PDB
Homo sapiens (human)Cell division protein kinase 2, p33 protein kinase
2AN'-[4-(2-amino-4-methyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-N,N-dimethylbenzene-1,4-diaminenon-polymer326.41Chemie (18K)
3AACETATE IONnon-polymer59.01Chemie (ACT)
4waterwater18.0143Chemie (HOH)
Sequence modifications
A: 1 - 298 (UniProt: P24941)
PDBExternal DatabaseDetails
Ace 0-ACETYLATION
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34002.5
Non-Polymers*Number of molecules2
Total formula weight385.5
All*Total formula weight34388.0
*Water molecules are not included.

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