3SUA

Crystal structure of the intracellular domain of Plexin-B1 in complex with Rac1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Ras-related C3 botulinum toxin substrate 1	polymer	184	20668.8	3	UniProt (P63000) Pfam (PF00071)	Homo sapiens (human)	Cell migration-inducing gene 5 protein, Ras-like protein TC25, p21-Rac1
2	D, E, F (D, E, F)	Plexin-B1	polymer	633	72628.0	3	UniProt (O43157) Pfam (PF08337) Pfam (PF20170)	Homo sapiens (human)	Semaphorin receptor SEP
3	G, I, K (A, B, C)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
4	H, J, L (A, B, C)	PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER	non-polymer		522.2	3	Chemie (GNP)

Sequence modifications

A, B, C: 1 - 177 (UniProt: P63000)

PDB	External Database	Details
Lys 178	-	expression tag
His 179	-	expression tag
His 180	-	expression tag
His 181	-	expression tag
His 182	-	expression tag
His 183	-	expression tag
His 184	-	expression tag

D, E, F: 1511 - 2135 (UniProt: O43157)

PDB	External Database	Details
Met 1503	-	expression tag
Gly 1504	-	expression tag
His 1505	-	expression tag
His 1506	-	expression tag
His 1507	-	expression tag
His 1508	-	expression tag
His 1509	-	expression tag
His 1510	-	expression tag
Thr 1625	Ser 1625	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	279890.5
Non-Polymers*	Number of molecules	6
	Total formula weight	1639.5
All*	Total formula weight	281530.0

*Water molecules are not included.