3SQO
PCSK9 J16 Fab complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proprotein convertase subtilisin/kexin type 9 | polymer | 540 | 57443.7 | 1 | UniProt (Q8NBP7) Pfam (PF00082) Pfam (PF18459) Pfam (PF18464) Pfam (PF18463) | Homo sapiens (human) | Neural apoptosis-regulated convertase 1, NARC-1, Proprotein convertase 9, PC9, Subtilisin/kexin-like protease PC9 |
| 2 | B (H) | J16 Heavy chain | polymer | 219 | 23762.5 | 1 | Homo sapiens (human) | ||
| 3 | C (L) | J16 Light chain | polymer | 214 | 23533.1 | 1 | Homo sapiens (human) | ||
| 4 | D (P) | PCSK9 prodomain | polymer | 122 | 13791.5 | 1 | UniProt (Q8NBP7) Pfam (PF05922) | Homo sapiens (human) | Neural apoptosis-regulated convertase 1, NARC-1, Proprotein convertase 9, PC9, Subtilisin/kexin-like protease PC9 |
| 5 | E, F, G, H (A, H, L, P) | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence modifications
A: 153 - 692 (UniProt: Q8NBP7)
| PDB | External Database | Details |
|---|---|---|
| Ile 474 | Val 474 | conflict |
| Glu 670 | Gly 670 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 118530.8 | |
| All* | Total formula weight | 118530.8 |
