3SQ3

Crystal Structure Analysis of the Yeast Tyrosyl-DNA Phosphodiesterase H182A Mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Tyrosyl-DNA phosphodiesterase 1	polymer	470	53985.0	4	UniProt (P38319) Pfam (PF06087)	Saccharomyces cerevisiae (Baker's yeast)	Tyr-DNA phosphodiesterase 1

Sequence modifications

A, B, C, D: 79 - 539 (UniProt: P38319)

PDB	External Database	Details
Met 78	-	initiating methionine
Ala 182	His 182	engineered mutation
Leu 540	-	expression tag
His 541	-	expression tag
His 542	-	expression tag
His 543	-	expression tag
His 544	-	expression tag
His 545	-	expression tag
His 546	-	expression tag
His 547	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	215939.8
All*	Total formula weight	215939.8

*Water molecules are not included.