3SQ0
DNA Polymerase(L561A/S565G/Y567A) Ternary Complex with dUpNpp Opposite dA (Mn2+)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DNA polymerase | polymer | 903 | 104490.9 | 1 | UniProt (Q38087) Pfam (PF03104) Pfam (PF00136) In PDB | Enterobacteria phage RB69 | Gp43 |
| 2 | T | 5'-D(*TP*CP*AP*AP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3' | polymer | 18 | 5525.6 | 1 | |||
| 3 | P | 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3' | polymer | 13 | 3951.6 | 1 | |||
| 4 | A | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE | non-polymer | 467.2 | 1 | Chemie (DUP) | |||
| 5 | A | MANGANESE (II) ION | non-polymer | 54.9 | 5 | Chemie (MN) | |||
| 6 | water | water | 18.0 | 302 | Chemie (HOH) |
Sequence modifications
A: 1 - 903 (UniProt: Q38087)
| PDB | External Database | Details |
|---|---|---|
| Ala 222 | Asp 222 | engineered mutation |
| Ala 327 | Asp 327 | engineered mutation |
| Ala 561 | Leu 561 | engineered mutation |
| Gly 565 | Ser 565 | engineered mutation |
| Ala 567 | Tyr 567 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 113968.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 741.8 | |
| All* | Total formula weight | 114710.0 |
