3SPF
Crystal Structure of Bcl-xL bound to BM501
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bcl-2-like protein 1 | polymer | 172 | 19676.6 | 1 | UniProt (Q07817) Pfam (PF02180) Pfam (PF00452) | Homo sapiens (Human) | Bcl2-L-1,Apoptosis regulator Bcl-X,Bcl2-L-1,Apoptosis regulator Bcl-X |
| 2 | B (A) | 4-(4-chlorophenyl)-1-[(3S)-3,4-dihydroxybutyl]-N-[3-(4-methylpiperazin-1-yl)propyl]-3-phenyl-1H-pyrrole-2-carboxamide | non-polymer | 525.1 | 1 | Chemie (B50) | |||
| 3 | C, D, E, F (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 4 | G (A) | water | water | 18.0 | 110 | Chemie (HOH) |
Sequence modifications
A: 1 - 84 (UniProt: Q07817)
A: 85 - 209 (UniProt: Q07817)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Phe 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19676.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 893.5 | |
| All* | Total formula weight | 20570.0 |
