3SML
Crystal structure of human 14-3-3 sigma C38N/N166H in complex with TASK-3 peptide and stabilizer Fusicoccin A aglycone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 14-3-3 protein sigma | polymer | 236 | 26577.9 | 1 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (human) | Epithelial cell marker protein 1, Stratifin |
| 2 | B (P) | TASK-3 peptide | polymer | 5 | 727.8 | 1 | UniProt (by SIFTS) (Q9NPC2) | Homo sapiens | |
| 3 | C (A) | Fusicoccin A aglycone | non-polymer | 408.5 | 1 | Chemie (FW1) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | E, F, G, H (A) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 6 | I, J (A, P) | water | water | 18.0 | 236 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Asn 38 | Cys 38 | engineered mutation |
| His 166 | Asn 166 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27305.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 541.2 | |
| All* | Total formula weight | 27846.9 |
