3SM2

The crystal structure of XMRV protease complexed with Amprenavir

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	gag-pro-pol polyprotein	polymer	132	14345.3	2	UniProt (Q9E7M1) Pfam (PF00077) In PDB	DG-75 Murine leukemia virus
2	A	{3-[(4-AMINO-BENZENESULFONYL)-ISOBUTYL-AMINO]-1-BENZYL-2-HYDROXY-PROPYL}-CARBAMIC ACID TETRAHYDRO-FURAN-3-YL ESTER	non-polymer		505.6	1	Chemie (478)
3		water	water		18.0	124	Chemie (HOH)

Sequence modifications

A, B: 1 - 125 (UniProt: Q9E7M1)

PDB	External Database	Details
Met -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	28690.6
Non-Polymers*	Number of molecules	1
	Total formula weight	505.6
All*	Total formula weight	29196.2

*Water molecules are not included.