3SL8
Crystal structure of the catalytic domain of PDE4D2 with compound 10o
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | polymer | 361 | 41523.9 | 4 | UniProt (Q08499) Pfam (PF00233) | Homo sapiens (human) | DPDE3, PDE43 |
| 2 | BA, CA, DA, E, H... (C, A, D, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 30 | Chemie (EDO) | |||
| 3 | EA, F, FA, G, PA... (C, A, D, B) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 4 | N, OA (A, D) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 5 | AA, IA, T, ZA (B, C, A, D) | 3-cyclopentyl 6-ethenyl 2-[(thiophen-2-ylacetyl)amino]-4,7-dihydrothieno[2,3-c]pyridine-3,6(5H)-dicarboxylate | non-polymer | 460.6 | 4 | Chemie (JN7) | |||
| 6 | GA, X (C, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 7 | HA, XA (C, D) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 8 | AB, BB, CB, DB (A, B, C, D) | water | water | 18.0 | 236 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 166095.5 | |
| Non-Polymers* | Number of molecules | 48 |
| Total formula weight | 4786.0 | |
| All* | Total formula weight | 170881.6 |
