3SI7
The crystal structure of the NBD1 domain of the mouse CFTR protein, deltaF508 mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Cystic fibrosis transmembrane conductance regulator | polymer | 285 | 31951.2 | 4 | UniProt (P26361) Pfam (PF00005) In PDB | Mus musculus (mouse) | CFTR, ATP-binding cassette sub-family C member 7, Channel conductance-controlling ATPase, cAMP-dependent chloride channel |
| 2 | A, B, C, D | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 4 | Chemie (ATP) | |||
| 3 | A, B, C, D | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
| 4 | A, B, C, D | ACETATE ION | non-polymer | 59.0 | 7 | Chemie (ACT) | |||
| 5 | water | water | 18.0 | 291 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 389 - 673 (UniProt: P26361)
| PDB | External Database | Details |
|---|---|---|
| Ser 388 | - | expression tag |
| - | Phe 508 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 127804.6 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 2636.5 | |
| All* | Total formula weight | 130441.1 |
