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3SE8

Crystal structure of broadly and potently neutralizing antibody VRC03 in complex with HIV-1 gp120

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(G)
HIV-1 Clade AE strain 93TH057 gp120polymer35339211.41Pfam (PF00516)
UniProt (by SIFTS) (Q0ED31)
Human immunodeficiency virus 1
2B
(H)
Heavy chain of antibody VRC03polymer23325294.51Homo sapiens
3C
(L)
Light chain of antibody VRC03polymer20923146.81Homo sapiens
4D, E, F, G, H...
(G)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.211Chemie (NAG)
5O, P, Q, R, S...
(G, H, L)
SULFATE IONnon-polymer96.18Chemie (SO4)
6T, V
(H)
1,2-ETHANEDIOLnon-polymer62.12Chemie (EDO)
7U
(H)
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer122.11Chemie (TRS)
8AA, BA, Z
(H, L, G)
waterwater18.0643Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight87652.8
Non-Polymers*Number of molecules22
Total formula weight3448.1
All*Total formula weight91100.8
*Water molecules are not included.

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