3SDY
Crystal Structure of Broadly Neutralizing Antibody CR8020 Bound to the Influenza A H3 Hemagglutinin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Hemagglutinin HA1 chain | polymer | 323 | 35506.9 | 1 | UniProt (Q91MA7) Pfam (PF00509) | Influenza A virus | |
| 2 | B (B) | Hemagglutinin HA2 chain | polymer | 176 | 20197.3 | 1 | UniProt (Q91MA7) Pfam (PF00509) | Influenza A virus | |
| 3 | C (H) | Antibody CR8020, Heavy Chain | polymer | 227 | 24344.1 | 1 | Homo sapiens | ||
| 4 | D (L) | Antibody CR8020, Light Chain | polymer | 216 | 23581.3 | 1 | Homo sapiens | ||
| 5 | E (C) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G22573RC) | |||
| 6 | F (D) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1057.0 | 1 | In PDB GlyTouCan (G82348BZ) | |||
| 7 | G (E) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 8 | H (F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 9 | I (G) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G32152BH) | |||
| 10 | J, K, L, M, N... (A, B, L) | SULFATE ION | non-polymer | 96.1 | 10 | Chemie (SO4) |
Sequence modifications
A: 11 - 329 (UniProt: Q91MA7)
B: 1 - 176 (UniProt: Q91MA7)
| PDB | External Database | Details |
|---|---|---|
| Ala 7 | - | expression tag |
| Asp 8 | - | expression tag |
| Pro 9 | - | expression tag |
| Gly 10 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 123 | Arg 468 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 103629.7 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 3711.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 960.6 | |
| All* | Total formula weight | 108301.7 |
