3SCK

Crystal structure of spike protein receptor-binding domain from a predicted SARS coronavirus civet strain complexed with human-civet chimeric receptor ACE2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Angiotensin-converting enzyme 2 chimera	polymer	603	69875.3	2	UniProt (Q56NL1) UniProt (Q9BYF1) Pfam (PF01401) In PDB	Paguma larvata (masked palm civet human)	ACE2, ACE-related carboxypeptidase, Angiotensin-converting enzyme homolog, ACEH, Metalloprotease MPROT15, Processed angiotensin-converting enzyme 2
2	E, F	Spike glycoprotein	polymer	185	21217.8	2	UniProt (P59594) Pfam (PF09408) In PDB	SARS coronavirus (SARS-CoV)	S glycoprotein, E2, Peplomer protein, Spike protein S1
3	A, B	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4	A, B	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)

Sequence modifications

A, B: 19 - 82 (UniProt: Q56NL1)
A, B: 83 - 615 (UniProt: Q9BYF1)

PDB	External Database	Details
His 616	-	expression tag
His 617	-	expression tag
His 618	-	expression tag
His 619	-	expression tag
His 620	-	expression tag
His 621	-	expression tag

E, F: 324 - 502 (UniProt: P59594)

PDB	External Database	Details
Pro 472	Leu 472	SEE REMARK 999
Arg 479	Asn 479	conflict
Gly 480	Asp 480	SEE REMARK 999
His 503	-	expression tag
His 504	-	expression tag
His 505	-	expression tag
His 506	-	expression tag
His 507	-	expression tag
His 508	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	182186.3
Non-Polymers*	Number of molecules	4
	Total formula weight	201.7
All*	Total formula weight	182388.1

*Water molecules are not included.