3SBY

Crystal Structure of SeMet-Substituted Apo-MMACHC (1-244), a human B12 processing enzyme

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Methylmalonic aciduria and homocystinuria type C protein	polymer	252	29357.6	2	UniProt (Q9Y4U1) Pfam (PF16690)	Homo sapiens (human)
2	C, D (A, B)	water	water		18.0	30	Chemie (HOH)

Sequence modifications

A, B: 1 - 244 (UniProt: Q9Y4U1)

PDB	External Database	Details
Mse 48	Leu 48	engineered mutation
Mse 83	Val 83	engineered mutation
Mse 107	Val 107	engineered mutation
Mse 164	Val 164	engineered mutation
Leu 245	-	expression tag
Glu 246	-	expression tag
His 247	-	expression tag
His 248	-	expression tag
His 249	-	expression tag
His 250	-	expression tag
His 251	-	expression tag
His 252	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	58715.2
All*	Total formula weight	58715.2

*Water molecules are not included.