3SBW

Crystal structure of the complex between the extracellular domains of mouse PD-1 mutant and human PD-L1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Programmed cell death protein 1	polymer	117	13218.8	2	UniProt (Q02242) Pfam (PF07686)	Mus musculus (mouse)	Protein PD-1
2	C (C)	Programmed cell death 1 ligand 1	polymer	222	25456.9	1	UniProt (Q9NZQ7) Pfam (PF07686) Pfam (PF08205)	Homo sapiens (human)	PD-L1, PDCD1 ligand 1, Programmed death ligand 1, B7 homolog 1, B7-H1
3	D, E, F (A, B, C)	water	water		18.0	130	Chemie (HOH)

Sequence modifications

A, B: 34 - 150 (UniProt: Q02242)

PDB	External Database	Details
Ser 83	Cys 83	engineered mutation
Leu 132	Ala 132	engineered mutation

C: 19 - 239 (UniProt: Q9NZQ7)

PDB	External Database	Details
Met 18	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	51894.5
All*	Total formula weight	51894.5

*Water molecules are not included.