3SBW
Crystal structure of the complex between the extracellular domains of mouse PD-1 mutant and human PD-L1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Programmed cell death protein 1 | polymer | 117 | 13218.8 | 2 | UniProt (Q02242) Pfam (PF07686) In PDB | Mus musculus (mouse) | Protein PD-1 |
| 2 | C | Programmed cell death 1 ligand 1 | polymer | 222 | 25456.9 | 1 | UniProt (Q9NZQ7) Pfam (PF07686) Pfam (PF08205) In PDB | Homo sapiens (human) | PD-L1, PDCD1 ligand 1, Programmed death ligand 1, B7 homolog 1, B7-H1 |
| 3 | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence modifications
A, B: 34 - 150 (UniProt: Q02242)
C: 19 - 239 (UniProt: Q9NZQ7)
| PDB | External Database | Details |
|---|---|---|
| Ser 83 | Cys 83 | engineered mutation |
| Leu 132 | Ala 132 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 18 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 51894.5 | |
| All* | Total formula weight | 51894.5 |
