3SAG
Crystal structure of the human RRP6 catalytic domain with D313N mutation in the active site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Exosome component 10 | polymer | 428 | 50354.7 | 2 | UniProt (Q01780) Pfam (PF01612) Pfam (PF00570) | Homo sapiens (human) | Rrp6, Autoantigen PM/Scl 2, P100 polymyositis-scleroderma overlap syndrome-associated autoantigen, Polymyositis/scleroderma autoantigen 100 kDa, PM/Scl-100, Polymyositis/scleroderma autoantigen 2 |
| 2 | C, D, F (A, B) | YTTRIUM (III) ION | non-polymer | 88.9 | 3 | Chemie (YT3) | |||
| 3 | E (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 228 | Chemie (HOH) |
Sequence modifications
A, B: 180 - 606 (UniProt: Q01780)
| PDB | External Database | Details |
|---|---|---|
| Ser 179 | - | expression tag |
| Asn 313 | Asp 313 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 100709.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 291.0 | |
| All* | Total formula weight | 101000.4 |
