3SAB
Crystal structure of wild-type HIV-1 protease in complex with AF78
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protease | polymer | 99 | 10815.8 | 2 | UniProt (O38732) Pfam (PF00077) | Human immunodeficiency virus 1 | |
| 2 | C (B) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 3 | D (B) | 3-hydroxy-N-[(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](3-phenylpropyl)amino}-1-phenylbutan-2-yl]benzamide | non-polymer | 588.7 | 1 | BIRD (PRD_000954) Chemie (F78) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 149 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: O38732)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 7 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21631.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 683.7 | |
| All* | Total formula weight | 22315.3 |
