3SA5
Crystal structure of wild-type HIV-1 protease in complex with AF69
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protease | polymer | 99 | 10815.8 | 2 | UniProt (O38732) Pfam (PF00077) | Human immunodeficiency virus 1 | |
| 2 | C, D (A) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 3 | E, F, G (B) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 4 | H (B) | N-{(2S,3R)-4-[(1,3-benzothiazol-6-ylsulfonyl)(3-phenylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl}-3-hydroxybenzamide | non-polymer | 615.8 | 1 | BIRD (PRD_000948) Chemie (A69) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 119 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: O38732)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 7 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21631.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1018.8 | |
| All* | Total formula weight | 22650.3 |
