3SA3
Crystal structure of wild-type HIV-1 protease in complex with AG23
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protease | polymer | 99 | 10815.8 | 2 | UniProt (O38732) Pfam (PF00077) | Human immunodeficiency virus 1 | |
| 2 | C, D, G (A, B) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 3 | E (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 4 | F (B) | N~2~-acetyl-N-[(2S,3R)-4-{(1,3-benzothiazol-6-ylsulfonyl)[(2S)-2-methylbutyl]amino}-3-hydroxy-1-phenylbutan-2-yl]-L-isoleucinamide | non-polymer | 602.8 | 1 | BIRD (PRD_000946) Chemie (23X) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: O38732)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 7 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21631.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 874.9 | |
| All* | Total formula weight | 22506.5 |
