3S8N
Crystal Structure of the Grb2 SH2 Domain in Complex with a pYXN-Derived Tripeptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Growth factor receptor-bound protein 2 | polymer | 117 | 13758.5 | 1 | UniProt (P62993) Pfam (PF00017) In PDB | Homo sapiens (human) | Adapter protein GRB2, Protein Ash, SH2/SH3 adapter GRB2 |
2 | B | pYAc5cN | polymer | 5 | 510.5 | 1 | |||
3 | A, B | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
4 | A | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
5 | water | water | 18.0 | 62 | Chemie (HOH) |
Sequence modifications
A: 53 - 163 (UniProt: P62993)
PDB | External Database | Details |
---|---|---|
His 164 | - | expression tag |
His 165 | - | expression tag |
His 166 | - | expression tag |
His 167 | - | expression tag |
His 168 | - | expression tag |
His 169 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 14269.0 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 347.2 | |
All* | Total formula weight | 14616.2 |