3S8I

The retroviral-like protease (RVP) domain of human DDI1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Protein DDI1 homolog 1	polymer	148	16415.0	2	UniProt (Q8WTU0) Pfam (PF09668) In PDB	Homo sapiens (human)
2	A, B	PHOSPHATE ION	non-polymer		95.0	3	Chemie (PO4)
3	A	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
4	A	UNKNOWN ATOM OR ION	non-polymer			1	Chemie (UNX)
5	B	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
6		water	water		18.0	175	Chemie (HOH)

Sequence modifications

A, B: 239 - 367 (UniProt: Q8WTU0)

PDB	External Database	Details
Met 220	-	initiating methionine
Gly 221	-	expression tag
Ser 222	-	expression tag
Ser 223	-	expression tag
His 224	-	expression tag
His 225	-	expression tag
His 226	-	expression tag
His 227	-	expression tag
His 228	-	expression tag
His 229	-	expression tag
Ser 230	-	expression tag
Ser 231	-	expression tag
Gly 232	-	expression tag
Leu 233	-	expression tag
Val 234	-	expression tag
Pro 235	-	expression tag
Arg 236	-	expression tag
Gly 237	-	expression tag
Ser 238	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	32830.1
Non-Polymers*	Number of molecules	6
	Total formula weight	453.1
All*	Total formula weight	33283.2

*Water molecules are not included.