3S85

Discovery of New HIV Protease Inhibitors with Potential for Convenient Dosing and Reduced Side Effects: A-790742 and A-792611.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Protease/reverse transcriptase	polymer	99	10830.8	12	UniProt (Q9QIQ7) Pfam (PF00077) UniProt (by SIFTS) (P12497) In PDB	Human immunodeficiency virus 1
2	B, C, E, H, I...	methyl N-[(2S)-1-[[(2S,3S,5S)-5-[[(2S)-2-(methoxycarbonylamino)-3,3-dimethyl-butanoyl]amino]-3-oxidanyl-6-phenyl-1-(4-pyridin-3-ylphenyl)hexan-2-yl]amino]-3,3-dimethyl-1-oxidanylidene-butan-2-yl]carbamate	non-polymer		703.9	6	BIRD (PRD_000796) Chemie (LK0)

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	129969.4
Non-Polymers*	Number of molecules	6
	Total formula weight	4223.2
All*	Total formula weight	134192.6

*Water molecules are not included.