3S7S
Crystal structure of human placental aromatase complexed with breast cancer drug exemestane
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cytochrome P450 19A1 | polymer | 503 | 57954.9 | 1 | UniProt (P11511) Pfam (PF00067) | Homo sapiens (human) | Aromatase, CYPXIX, Cytochrome P-450AROM, Estrogen synthase |
| 2 | B (A) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 3 | C (A) | (8alpha,10alpha,13alpha)-6-methylideneandrosta-1,4-diene-3,17-dione | non-polymer | 296.4 | 1 | Chemie (EXM) PubChem (16667705) PubChem (16757897) PubChem (176519887) PubChem (60198) PubChem (51546384) PubChem (51546385) PubChem (51546386) PubChem (46783392) PubChem (66613097) PubChem (66613111) PubChem (73265344) PubChem (73707497) PubChem (4460995) PubChem (129010006) PubChem (117072350) PubChem (124289613) PubChem (124428799) PubChem (124836523) PubChem (125181203) PubChem (132000514) PubChem (146359540) PubChem (168322339) PubChem (145379415) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 57954.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 912.9 | |
| All* | Total formula weight | 58867.8 |
