3S7S
Crystal structure of human placental aromatase complexed with breast cancer drug exemestane
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cytochrome P450 19A1 | polymer | 503 | 57954.9 | 1 | UniProt (P11511) Pfam (PF00067) | Homo sapiens (human) | Aromatase, CYPXIX, Cytochrome P-450AROM, Estrogen synthase |
| 2 | B (A) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 3 | C (A) | (8alpha,10alpha,13alpha)-6-methylideneandrosta-1,4-diene-3,17-dione | non-polymer | 296.4 | 1 | Chemie (EXM) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 57954.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 912.9 | |
| All* | Total formula weight | 58867.8 |
