3S7A
Human dihydrofolate reductase binary complex with PT684
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Dihydrofolate reductase | polymer | 186 | 21349.5 | 1 | UniProt (P00374) Pfam (PF00186) In PDB | Homo sapiens (human) | |
| 2 | A | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 3 | A | 4-({5-[(2,4-diaminopteridin-6-yl)methyl]-5H-dibenzo[b,f]azepin-2-yl}oxy)butanoic acid | non-polymer | 469.5 | 1 | Chemie (684) | |||
| 4 | water | water | 18.0 | 21 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21349.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 949.8 | |
| All* | Total formula weight | 22299.3 |
