3S57
ABH2 cross-linked with undamaged dsDNA-1 containing cofactors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 | polymer | 204 | 23267.6 | 1 | UniProt (Q6NS38) Pfam (PF13532) | Homo sapiens (human) | Alkylated DNA repair protein alkB homolog 2, Oxy DC1 |
| 2 | B (B) | 5'-D(*CP*TP*GP*TP*CP*AP*TP*CP*AP*CP*TP*GP*CP*G)-3' | polymer | 14 | 4231.8 | 1 | |||
| 3 | C (C) | 5'-D(*TP*CP*GP*CP*AP*GP*TP*GP*AP*TP*GP*AP*CP*A)-3' | polymer | 14 | 4304.8 | 1 | |||
| 4 | D (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 5 | E (A) | 2-OXOGLUTARIC ACID | non-polymer | 146.1 | 1 | Chemie (AKG) | |||
| 6 | F, G (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | H (B) | propane-1-thiol | non-polymer | 76.2 | 1 | Chemie (XL3) | |||
| 8 | I, J, K (A, B, C) | water | water | 18.0 | 338 | Chemie (HOH) |
Sequence modifications
A: 56 - 258 (UniProt: Q6NS38)
| PDB | External Database | Details |
|---|---|---|
| Met 55 | - | expression tag |
| Ser 67 | Cys 67 | engineered mutation |
| Ser 165 | Cys 165 | engineered mutation |
| Cys 169 | Gly 169 | engineered mutation |
| Ser 192 | Cys 192 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 31804.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 461.4 | |
| All* | Total formula weight | 32265.6 |
