3S3I
p38 kinase crystal structure in complex with small molecule inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 14 | polymer | 349 | 40034.8 | 1 | UniProt (Q16539) Pfam (PF00069) | Homo sapiens (human) | MAP kinase 14, MAPK 14, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAP kinase MXI2, MAX-interacting protein 2, Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, SAPK2A |
| 2 | B (A) | 3-(3-tert-butyl[1,2,4]triazolo[4,3-a]pyridin-7-yl)-N-cyclopropyl-4-methylbenzamide | non-polymer | 348.4 | 1 | Chemie (CQ0) | |||
| 3 | C (A) | water | water | 18.0 | 230 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40034.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 348.4 | |
| All* | Total formula weight | 40383.2 |
