3S37
Structural basis for the function of two anti-VEGF receptor antibodies
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | 1121B Fab light chain | polymer | 214 | 23245.8 | 1 | Mus musculus Homo sapiens (mouse human) | ||
| 2 | B (H) | 1121B Fab heavy chain | polymer | 221 | 23324.1 | 1 | Mus musculus Homo sapiens (mouse human) | ||
| 3 | C (X) | Vascular endothelial growth factor receptor 2 | polymer | 122 | 13504.3 | 1 | UniProt (P35968) Pfam (PF00047) | Homo sapiens (human) | VEGFR-2, Fetal liver kinase 1, FLK-1, Kinase insert domain receptor, Protein-tyrosine kinase receptor flk-1 |
Sequence modifications
X: 220 - 338 (UniProt: P35968)
| PDB | External Database | Details |
|---|---|---|
| Ala 217 | - | expression tag |
| Asp 218 | - | expression tag |
| Pro 219 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 60074.3 | |
| All* | Total formula weight | 60074.3 |
