3S11

Crystal structure of H5N1 influenza virus hemagglutinin, strain 437-10

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E (A, C, E)	Hemagglutinin HA1 chain	polymer	331	37140.8	3	UniProt (Q9EA62) Pfam (PF00509) UniProt (by SIFTS) (Q9Q0U6)	Influenza A virus
2	B, D, F (B, D, F)	Hemagglutinin HA2 chain	polymer	182	20937.1	3	UniProt (Q9EA62) Pfam (PF00509) UniProt (by SIFTS) (Q8QPL1)	Influenza A virus
3	G, I (G, I)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
4	H (H)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
5	J, M, O (A, C, E)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
6	K, N, P (A, C, E)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
7	L (A)	TRIS(HYDROXYETHYL)AMINOMETHANE	non-polymer		163.2	1	Chemie (TAM)
8	Q, R, S, T, U... (A, B, C, D, E...)	water	water		18.0	133	Chemie (HOH)

Sequence modifications

A, C, E: 11 - 326 (UniProt: Q9EA62)

PDB	External Database	Details
Asp 3	-	expression tag
Leu 4	-	expression tag
Gly 5	-	expression tag
Ser 6	-	expression tag
Ala 7	-	expression tag
Asp 8	-	expression tag
Pro 9	-	expression tag
Gly 10	-	expression tag

B, D, F: 1 - 176 (UniProt: Q9EA62)

PDB	External Database	Details
Arg 177	-	expression tag
Ser 178	-	expression tag
Leu 179	-	expression tag
Val 180	-	expression tag
Pro 181	-	expression tag
Arg 182	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	174233.9
Branched	Number of molecules	3
	Total formula weight	1435.3
Non-Polymers*	Number of molecules	7
	Total formula weight	1103.1
All*	Total formula weight	176772.3

*Water molecules are not included.