3RZL

Duplex Interrogation by a Direct DNA Repair Protein in the Search of Damage

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2	polymer	208	23721.1	2	UniProt (Q6NS38) Pfam (PF13532) In PDB	Homo sapiens (human)	Alkylated DNA repair protein alkB homolog 2, Oxy DC1
2	B, E	5'-D(*AP*TP*GP*TP*AP*TP*CP*AP*CP*TP*GP*CP*G)-3'	polymer	13	3966.6	2
3	C, F	5'-D(*TP*CP*GP*CP*AP*GP*TP*IP*AP*TP*AP*CP*A)-3'	polymer	13	3960.6	2
4	B, E	propane-1-thiol	non-polymer		76.2	2	Chemie (XL3)
5		water	water		18.0	18	Chemie (HOH)

Sequence modifications

A, D: 56 - 261 (UniProt: Q6NS38)

PDB	External Database	Details
Ser 54	-	expression tag
His 55	-	expression tag
Ser 67	Cys 67	engineered mutation
Ser 165	Cys 165	engineered mutation
Cys 169	Gly 169	engineered mutation
Ser 192	Cys 192	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	63296.6
Non-Polymers*	Number of molecules	2
	Total formula weight	152.3
All*	Total formula weight	63448.9

*Water molecules are not included.