3RZK
Duplex Interrogation by a Direct DNA Repair Protein in the Search of Damage
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 | polymer | 209 | 23778.2 | 1 | UniProt (Q6NS38) Pfam (PF13532) | Homo sapiens (human) | Alkylated DNA repair protein alkB homolog 2, Oxy DC1 |
| 2 | B (B) | 5'-D(*CP*TP*GP*TP*CP*TP*(EDA)P*AP*CP*TP*GP*CP*G)-3' | polymer | 13 | 3966.6 | 1 | |||
| 3 | C (C) | 5'-D(*TP*CP*GP*CP*AP*GP*TP*TP*AP*GP*AP*CP*A)-3' | polymer | 13 | 3975.6 | 1 | |||
| 4 | D (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 5 | E (A) | 2-OXOGLUTARIC ACID | non-polymer | 146.1 | 1 | Chemie (AKG) | |||
| 6 | F (B) | propane-1-thiol | non-polymer | 76.2 | 1 | Chemie (XL3) | |||
| 7 | G, H (A, B) | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence modifications
A: 56 - 261 (UniProt: Q6NS38)
| PDB | External Database | Details |
|---|---|---|
| Gly 53 | - | expression tag |
| Ser 54 | - | expression tag |
| His 55 | - | expression tag |
| Ser 67 | Cys 67 | engineered mutation |
| Ser 165 | Cys 165 | engineered mutation |
| Cys 169 | Gly 169 | engineered mutation |
| Ser 192 | Cys 192 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 31720.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 277.2 | |
| All* | Total formula weight | 31997.6 |
