3RZC
Structure of the self-antigen iGb3 bound to mouse CD1d and in complex with the iNKT TCR
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Antigen-presenting glycoprotein CD1d1 | polymer | 285 | 32632.7 | 1 | UniProt (P11609) Pfam (PF16497) Pfam (PF07654) In PDB | Mus musculus (mouse) | |
2 | B | Beta-2-microglobulin | polymer | 99 | 11660.4 | 1 | UniProt (P01887) Pfam (PF07654) In PDB | Mus musculus (mouse) | |
3 | C | Valpha14 | polymer | 209 | 23055.6 | 1 | Mus musculus Homo sapiens | ||
4 | D | Vbeta8.2 | polymer | 241 | 27027.0 | 1 | Mus musculus Homo sapiens | ||
5 | E, F | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
6 | G | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G70885YM) | |||
7 | A | N-[(2S,3R,4E)-1-{[alpha-D-galactopyranosyl-(1->3)-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl]oxy}-3-hydroxyoctadec-4-en-2-yl]hexacosanamide | non-polymer | 1164.6 | 1 | Chemie (LGN) | |||
8 | water | water | 18.0 | 48 | Chemie (HOH) |
Sequence modifications
A: 1 - 279 (UniProt: P11609)
B: 1 - 99 (UniProt: P01887)
PDB | External Database | Details |
---|---|---|
His 201 | Asp 219 | conflict |
His 280 | - | expression tag |
His 281 | - | expression tag |
His 282 | - | expression tag |
His 283 | - | expression tag |
His 284 | - | expression tag |
His 285 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ala 85 | Asp 105 | variant |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 94375.6 | |
Branched | Number of molecules | 3 |
Total formula weight | 1581.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 1164.6 | |
All* | Total formula weight | 97121.7 |