3RVF
FXR with SRC1 and GSK2034
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bile acid receptor | polymer | 232 | 27048.0 | 1 | UniProt (Q96RI1) Pfam (PF00104) | Homo sapiens (human) | FXR, Farnesoid X-activated receptor, Farnesol receptor HRR-1, Nuclear receptor subfamily 1 group H member 4, Retinoid X receptor-interacting protein 14, RXR-interacting protein 14 |
| 2 | B (B) | Nuclear receptor coactivator 1 | polymer | 21 | 2650.0 | 1 | UniProt (Q15788) | Homo sapiens | SRC1, NCoA-1, Class E basic helix-loop-helix protein 74, bHLHe74, Protein Hin-2, RIP160, Renal carcinoma antigen NY-REN-52, Steroid receptor coactivator 1 |
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | 5-(4-{[3-(2,6-dichlorophenyl)-5-(propan-2-yl)-1,2-oxazol-4-yl]methoxy}phenyl)-1H-indole-2-carboxylic acid | non-polymer | 521.4 | 1 | Chemie (034) | |||
| 5 | E (A) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
A: 243 - 472 (UniProt: Q96RI1)
| PDB | External Database | Details |
|---|---|---|
| Gly 241 | - | expression tag |
| Ser 242 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29698.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 617.5 | |
| All* | Total formula weight | 30315.5 |
