3RR3

Structure of (R)-flurbiprofen bound to mCOX-2

Entity

Chain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
A, B, C, DProstaglandin G/H synthase 2polymer56064337.34
UniProt (Q05769)
Pfam (PF00008)
Pfam (PF03098)
Mus musculus (mouse)@PDBjCyclooxygenase-2, COX-2, Glucocorticoid-regulated inflammatory cyclooxygenase, Gripghs, Macrophage activation-associated marker protein P71/73, PES-2, PHS II, Prostaglandin H2 synthase 2, PGH synthase 2, PGHS-2, Prostaglandin-endoperoxide synthase 2, TIS10 protein
N-ACETYL-D-GLUCOSAMINEnon-polymer221.216
PROTOPORPHYRIN IX CONTAINING FEnon-polymer616.54
(2R)-2-(3-fluoro-4-phenyl-phenyl)propanoic acidnon-polymer244.34
B-OCTYLGLUCOSIDEnon-polymer292.46
waterwater18.0241

Sequence viewer

Contents of the asymmetric unit

PolymersNumber of chains4
Total molecular weight257349.3
Non-Polymers*Number of molecules30
Total molecular weight8736.5
All*Total molecular weight266085.9
*Water molecules are not included.