3RR3
Structure of (R)-flurbiprofen bound to mCOX-2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Prostaglandin G/H synthase 2 | polymer | 560 | 64337.3 | 4 | UniProt (Q05769) Pfam (PF00008) Pfam (PF03098) | Mus musculus (mouse) | Cyclooxygenase-2, COX-2, Glucocorticoid-regulated inflammatory cyclooxygenase, Gripghs, Macrophage activation-associated marker protein P71/73, PES-2, PHS II, Prostaglandin H2 synthase 2, PGH synthase 2, PGHS-2, Prostaglandin-endoperoxide synthase 2, TIS10 protein |
| 2 | AA, BA, CA, E, EA... (C, D, A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 16 | Chemie (NAG) | |||
| 3 | FA, H, P, X (D, A, B, C) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) | |||
| 4 | DA, I, Q, W (D, A, B, C) | (2R)-2-(3-fluoro-4-phenyl-phenyl)propanoic acid | non-polymer | 244.3 | 4 | Chemie (FLR) | |||
| 5 | GA, J, K, R, Y... (D, A, B, C) | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 6 | Chemie (BOG) | |||
| 6 | IA, JA, KA, LA (A, B, C, D) | water | water | 18.0 | 241 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 257349.3 | |
| Non-Polymers* | Number of molecules | 30 |
| Total formula weight | 8736.5 | |
| All* | Total formula weight | 266085.9 |
